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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294e2df625b6f43bbdac28619ad5ded8f9f83d14900cbff50deb3c8deb996077' 
  AND token = '3G2ntqow7VmlTF9A9t6/xftmu1f4dtb+YkBWKtU83Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}