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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53c739b4d284b3e659380bcff7ca0d89ba9a29fd09892255bb846f7e3e8cd2c3' 
  AND token = 'edJrIaP6W/kc+/bM6yPT0xQ9Eidx+5DzSQYjwC4s9Es=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}