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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6080347aaab63e132b6d6f970ececfb6c7669f76a68e2bd0210a54dd384d5ca' 
  AND token = 'yE0upkqYoAAVonsAOzHVez+Ta1o6360UAh78ttc2Fdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}