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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '83756f22acf7f498990d3d43d34fbfb924cf907819c553c30a80bb74f33ce179' 
  AND token = 'hwiuWMsl+vIR5XJdsqjM3Iu0SVnytCMErEFAeBNmKEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}