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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d4157f2cf8b31be186e4126296b07e50b7a87a51208494b265ad8973dd5ecf0' 
  AND token = 'pvmd6cJsyQ8w238Y2iZXEc2fkVlAQoRlx4wLhf5VZjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}