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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a48cc9a25c9e81ed529c3430a80f471f8b7d769e20774e73ff5ff52b8f7dced' 
  AND token = 'iIGf3a4zTiMC+ymfO0dy3onCgPi5R8/IQziKUpBiu8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}