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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c77f8c0983ad868a58389b6cc7793663ac04d5250b98327a5f1666b43d0c6b9' 
  AND token = 'joxpJR51gv+eNVzEW9JXNnOjGfsWTsGwcW4j5jJwDXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}