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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ddfbf75f953def54d057286804338cf0b229f28056b76e77912d2e88c4403f' 
  AND token = 'HtutPq6p7tpqOHjAKQiPM7v0J3TYpcw1aCsP/UY6bSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}