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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '021a9d4c06cc4de72460d4b2514eff45fd26a1e461b22ed5825e062d82359aee' 
  AND token = 'aQBoI7zxsauormAESL/8H4bO6x3msGg/+bb5/38LWBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}