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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22564e0f980a6fc7ea83445f86b0306b8d5b3f65e5008290e6fc04264bbbfbd' 
  AND token = '+owR+hUMRL8ygsfOYypsaf13FOjTjPGUH6XDVY6ucoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}