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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4207a6e8d15b33a2c503a71f4c2bae8c00c844611a76f04b3d4b359cef5f6033' 
  AND token = 'Brs0nb+aDlvfibmnyYiA3ImpXViGFZMza1gYpOpTGuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}