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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a280ee9f76557c2855373517ed525b8c6681b9d7aa36e20f89341885251b2d70' 
  AND token = 'LGYTZTdA8xrXsUMCyhFfSMDxE2mUknGdTVxoGWf24ds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}