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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5300ec359258adae86d9615199520d7224422339b5440eb88c332c39664d9389' 
  AND token = '8LmdbiXBQtVt0HkDxTJC2aCIfKoSB3YXHgNqjeX5Fzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}