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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2730a2ce86e146576b3e1f89e5aefb5b1bf408dc7858af7ee00956ffd2428a0' 
  AND token = 'F3Nn/2GI+Md8YSBBTlhVMduOFFuMdUfC1FMcoTxB2f4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}