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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e3bdb60422007a4aeb58724e84afad3799ed4ea1f12b0248ec604a1d6c5f80' 
  AND token = 'vN0MgwJ9ralz0SF3UzlnJsdIL5GsdsaGHRkB6W99gkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}