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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '081e0687b16ce87cb5dd3c3ad084583bb6f8b0840e6db245d493f1110345d365' 
  AND token = 'ohjNeinT8g0UZTYT3s8FYdOM8t+HwSAYoxkxybquUas=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}