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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b74de476343d9dd69d0b704475c8c19a11650105d2ed580c18301fd85a5014' 
  AND token = 'nv2HInVd+mO7Ics6r7zmeVJKIM0/7Ipzt89Yl84ErCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}