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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a90c22e23dc214e79a92e1a184d587c4646564da2b1de1a2202bcd99f854201' 
  AND token = 'grwsfieDC37LiRBYdsYpc8k698y3wSt74K/A8tkVX+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}