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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8a9fa476982025eddd64e3ba2b01641a0cbfc0bda96da81520e8a470c8b3ba' 
  AND token = 'T+kdEUK/1MIVqZH4SzUMASe8s+zdf8tX+L8SjI87RKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}