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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a2eff6e29421016ae55b2b195d90106aad775b68ecb46e822b03b681d19e4d' 
  AND token = 'OGwGi7Co4WIoE0OX9PVHZiSBcCi2dWzDcO/c18G5Eeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}