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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e8b37a4e2af86b7dbcaecd1680658b8f535d8025a8568034badab9e6f4f1ad' 
  AND token = 'P996Sn/thVhmNgosFKYcEjH3oZ84t4VA3dWhS8CuEj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}