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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c025e5c38858085987f2e9ca9db5b506dd1ec0c10fe8d26d5db0301acf7fb21f' 
  AND token = 'JFE+RgNhx0wD5sL1uuJlTEoow68lW8jgCeT5cAsGUVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}