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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe957f7e0d7396db60ab1a8d023ff29f42cd03de451874692c3f9d4d53c8349' 
  AND token = 'DQ7CmgiSFxN80YrNaRMDWXcB5qVO+ay3i9FENfGBYQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}