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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6cfa46294c26d332510818e70014294c962fa79e7e4dd39f97d7173ce0a5cd' 
  AND token = '7wQC2QAS+NWPGdpYMOp74fNtGAj9Ya34lv6Ul2AJvAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}