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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2690ca6d4e164268489489395a440114a72f4a02e69de3b28904bb2df08496' 
  AND token = 'TApN419HeDIJDQTD1vKAPiMErW/M2kq0RH3Q/49BVoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}