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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd505ad9fe7c9fe544f709bb70c54c7fc33a59c3b13833edaf1c44f9d461b2e66' 
  AND token = 'Js8rbIfipj7bHwMp5vyrfBzce6RUSgKay4KJVleLzus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}