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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61d5d61876b47933d9eec63640d8003e9499c17134218de7f9958e40e4a11a6b' 
  AND token = 'kxFYcUSMQaCHHJ51buyCg+RuMq0kJcJmNjuRXO6iVGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}