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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7cae4880904b9b6b38b8131931582ca161e4a9f48c2ef593226f7214c738e51' 
  AND token = 'SDDrDCiJReO/2Dp7xOVOhxAMC8uL55PU/2e2rdodJys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}