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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4e52a38ce206e9dede94012c7e1aadbcf6b40734deb5d2f616e171088edf4c' 
  AND token = 'V6cpQRi6hhNjhRkq9BnMDUImIo5ecV7MbUlvRjfU9jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}