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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4902061b77c8c8c9e4f832ba96e9ab6633373f938fbe96c9d5a66f3092793b' 
  AND token = 'VZ/lds8CyU2RDoT/To/QTFIAgnQKM9fIKMXVt6eK4UI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}