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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d1ddc8d412a66c81e67719cbd0d046f47e051cf8cc11a0429e69c96a2338e57' 
  AND token = 'vcHPvYqLWMg5Yv+9pieZY0HLs+l19Qk6qHlD/D/pcjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}