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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f5c163b81dc56221c40279b1f872053c49b20d23394b6ce45d13f5a379f8794' 
  AND token = 'OurQgYggPXbgtRPNnS8KwR69h2k06bocX389Z/j1diM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}