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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8927a67431b034c97f47dad9f45d2c7c5f7f248124ec44c810fc42bb2f752a' 
  AND token = 'RGUKnvO9qrLx6DQR7NPNU14PC12rd4kcpeE0IjVUtJc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}