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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd16618cdecdd3614db10dac0981b5fefbfef5d023685e553fa9a8d86e39f56d' 
  AND token = 'kupOiMjc1X/BlfpAMdm98MjXVIO3FLbr0QbXBoXQxZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}