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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7621ef192432fc7a792802ff2929d46ba51fee2214ae03ce6a7d59742f001a68' 
  AND token = '8W00t1kbZSKaIgUEcLjeS1bWLQvjjHJYtq0UF6Q//b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}