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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8b4894a1f5854b1546651e3daaec8369329aea7e3689a3432f0595c099e7f0' 
  AND token = 'p/5hDvjM1AyvVx6Vbfi5P3u1q1vw6AfQSakr6XVCeiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}