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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b8f6c9e653c34c4d4255c9d06864760700ce5dc6f605b319a67c3e6d5984fa1' 
  AND token = 'ESs6tR9KeaHqdICP6X/G8zyy5P6TnqwWnq4RWvZqgzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}