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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64bbfd5ebd029f5bd9384e8a922f74ceb472b48c22fd9bd6a98d95cdbfcad131' 
  AND token = 'S8rHNorCJCJN+XMuB+Li4otJ3feVFpe7Woe3XyiaiLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}