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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f889ffcc0619441bdb19ac664d0c5cf0600bf780d2d52f3a133fe309407ff2' 
  AND token = 'HcnqZIoWrO1GDFM4/fIgYZTUdxj4SLVTSXO9NVoLl+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}