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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e35c176a91b725816c71e624b7bf22bed6ca457f4060ab8ebb248774d67e4a4b' 
  AND token = 'wfAxUrjBYheMenHhOcm+0SwWUrubdm9d2RkZ7M7+Agg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}