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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d3882295504409a5aff0c21ad697da0943f7d94adddcd44e33a33d45dd6e022' 
  AND token = '5njXNp1nrkAqxvb1pMG7kbnPN3jNzSBiNiXIiV1CBcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}