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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee27a8907b990a3bc3fa19ed228a8a8262604c4db7470ff8807108320f5e41f0' 
  AND token = 'ODqMRkby5TLN/Y4bp84xTwXI/InRxlOlTd3hcLtO80Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}