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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d4eb7acb8790dcb8c78f965ec230eaa29e85b7fd88c86245c26cefed0b2778' 
  AND token = '7q0imAGxXBTiShFiyuDr3vvGDDH/dEABy81ggV+Br2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}