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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c463ba8261fe417f6f7a80876808280ba16a6d350344ee1ee6c9faef1ab7b64' 
  AND token = '0R/9ANsyKbomzO+PjPYHP5pW6zL61l817P0DzEydFQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}