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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f61a2af2d6367bf2a7aad064192d8cde0e1a3787ede627c21a295c4b50d250bb' 
  AND token = 'i9YV0jhiOsYrpXY2SPQlMpyQg4iwDeIqjqg8yTn1lY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}