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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af42ee226f23a6847e1d8f7ac4db4f231cd2eabde39ef0c8372d0aaa7be7daaf' 
  AND token = '8ohSiHChU062Zk+RgT2zGKQwwaVSyR93UrehYH8rE9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}