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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e1d2a88423f94ad65f1511368bc50ea0a342b31158fceaa4b8545980ac179f' 
  AND token = 'EuzJSLqMHOlJM6k+rJ4q1/DEkCElSE0aNXjxlmfEcoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}