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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07845678bf214aa5d231c8541c99ad30d748848e3a659746d838013c4cebb3f1' 
  AND token = '71KmCq9u8ju5d8DyFX89JQzjTEv+kEv+XTjk+YWxHlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}