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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9665034c43d3d2b442c8236339c8c2a489aa7b38cf7e418ae041c3df973e0812' 
  AND token = 'XRVAREdF+S1y0qq1rVNrHqIcL0i0wUAqpgZGzUEqPnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}