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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4cd2eac0cc393157d20ca21c9c3012f2db1b8ddb271a01734794d81eac6c66d' 
  AND token = '6fQHTTBLEiyAu59Y0kTfLK6M3Ykhzu5VjDaKCaNfdEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}